måndag 15 mars 2010

Nanoparticles to battle nail fungus

I spend quite a bit of time online gathering information on this topic. I am searching high and low for a new and more effective treatment, none seem to be on the market yet, although a couple of things are are under development, such as the NB-002 drug, by NanoBio corporation. You can read for yourselves here http://www.nanobio.com/Dermatology/Onychomycosis.html .

This substance apparently uses droplets of oil that are super-tiny, to put it mildly. It is nanotechnology we are talking about, and these nanoparticles are supposed to, due to their small size, be able to enter the skin through pores and follicles around the nail, carrying with them dissolved terbinafine.

This sounds good, since the number one problem is actually getting the drug to the fungus, which is in the nail bed, safely hidden behind the nail. Research so far looks promising. One must rememeber that the first studies on a new drug are always conducted by the producers themselves, so the results may be biased, but still, the results look promising. One study can be viewed at http://www.drugs.com/clinical_trials/nanobio-corporation-completes-interim-analysis-phase-2-clinical-trial-onychomycosis-3624.html .

Another one is here, and it reports on the cure rates:


This drug is in phase 3 trials, meaning testing on human subjects in a larger scale, and it is the last phase before hitting the pharmacies (in some cases it can be sold and used outside of the clinical trial environemnt even before ending phase 3 trials, but so far NB-002 cannot be obtained over the counter).

When it hits the shelves, if I am still not problem-free, I will give it a try.

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