söndag 23 oktober 2016
Some short words on the current state of things
måndag 11 augusti 2014
Some more positive words on oral terbinafine (Lamisil)
Oral terbinafine in the form of Lamisil pills has in trials been shown to have a 50 percent cure rate which leaves half of us still looking around. I did however come across this interesting article written by Nardo Zaias who apparently have many decades of experience in the field. According to him terbinafine has a delayed effect and a pulsed treatment regimen can be 100 % effective over the course of 12 months.
"With 20 patients, who had their nail bed 100% involved received one week of treatment every month. After approximately one year all patients were cured. This was followed by another set of patients, who also had 100% of their NB involved and who also received one week of treatment every two months."
Further on in the article it says "All patients were cured again in one year. Another set of patients received the same treatment regimen, one week every 3 months, and 95% of them cured after a year. Fatigued but encouraged, the last set of patients received one week of treatment every 4 months, about 50 % were cured. Meaning that the beneficial depot antimycotic effect lasts at least for 3 months. "
The article can be read at http://www.jscimedcentral.com/Dermatology/Articles/dermatology-1-1003.php
For those who read my posts it may seem I am a fierce opponent of alternative medicine, I am not. But when I am to put my mind to something that may take 3-6-12 months, really do everything right I want my chances of success to be as good as possible. And this is not a point that can be discussed really: in order to find out if a drug works you have to T E S T the drug scientifically and double-blind scientific trials are infinitely more reliable than my grandmother's words, my own gut feeling or stories told by friends.
lördag 30 november 2013
Formula 3 antifungal by TetraCorp
I have read a couple of posititve reviews online as you will always find no matter what product you research but the mixture itself seems interesting when you look closer at it. It contains tolftanate which is a completely legit antifungal, in trials it has been shown to be effective when compared to other antifungals, see http://www.ijdvl.com/article.asp?issn=0378-6323;year=1990;volume=56;issue=2;spage=130;epage=131;aulast=Rajendran .
It seems to be slightly less effective than azoles (itraconazole, clotrimazole) which in turn have been shown to be less effective than terbinafine, still the top dog when it comes to efficently treating fungal skin and nail infections. But apparently they have managed to make tolftanate oil-soluble and dissolve it in jojoba oil which should logically make for a better drug transfer, always the issue when it comes to nail fungus. I like to think that this should be able to peneterate a clean, thinly filed down nail and get to work.
A problem (for me) is that this is only sold in physician's offices and the website tells you to consult your doctor. I have found a couple of places on amazon and ebay that sell the stuff second-hand but they will not ship outside the US....
Either way, that might also be worth a try for those of us who have tried and failed with a lot of treatment methods. If anybody living in the US would like to help me get hold of a bottle of this stuff I would be grateful of course, I can compensate you for your efforts and expenses if you will have it sent to me.
Same goes of course for luliconazole, sold as lulifin in India and Lulicon/Rurikon in Japan, I am extra interested in that stuff.
New topical medication on market: Jublia topical solution
torsdag 24 oktober 2013
Luliconazole
It is also being sold in Japan under the name Lulicon, when you research it using search engines you should try both the spelling "lulicon" and "rurikon" (some completely unrelated pages with Japanese dress-up stuff might come up.....). It is manufactured by the company Pola Pharma and I have tried obtaining it through their Australian branch who referred me to the Japanese company who in turn let me know that they cannot sell drugs to countries where it has not passed all the tests (in simple terms that was the message, it is not being sold here so they can't send it here either).
I am curious about this one since it is A: something I haven't tried, B: it is actually real medicine and not something someone cooked up in their basement and sold over the internet with sexy words like "essential oils", "all natural", "homeopathic remedy" and so on. And C: one can find a couple promising studies online, like at http://www.sciencedomain.org/abstract.php?iid=234&id=14&aid=1918#.Uml8I_lkODg where it is stated that for mild skin infections Luliconazole cream and Terbinafine cream were equally efficient, here it must be remembered that Terbinafine is still the top dog when it comes to antifungals.
So I want to try the lulicon/rurikon/lulifin and try it on my toenail fungus, I am kind of reaching out here. Anybody who lives in India or Japan or knows another way to obtain medicine from there is welcome to contact me, it would be appreciated
torsdag 25 april 2013
My current status
The reason for this is pretty much that I don't have much to write. My toenails have been the area of battle for the last couple of years and I can't say I have had success. I kept treating them with the same procedure as described in previous posts, mechanical debridement of the nail by filing it down to as thin as possible using an electrical drill with a sander tip, then, with the nail either gone or a tenth of it's normal thickness I would apply Lamisil Once regularly. Lamisil is a proper medicine, there is nothing alternative about it. It went through the normal processes, years upon years of trials and research, millions and millions spent by a pharmaceutical company and to this day it (terbinafine) is still the substance that has the highest percentage of success in fungus sufferers. In other words: as legit as something can ever be.
It cured my fingernails 100 %, no trace of infection and I have been healthy for over 2 years now, see my posts from early 2010: http://battlenailfungus.blogspot.se/2010/03/new-photos.html and from late 2010: http://battlenailfungus.blogspot.se/2010/08/my-procedure.html . My toenails have not had the same success.
Working with toenails is more difficult, your back hurts as you carefully work your tools and try to see what you are doing while not hurting yourself. It also proved more difficult for me to treat them twice a day because it is more of a hassle taking off your shoes and socks when you realize you forgot to apply the gel.
A third thing: socks and shoes make for a warm, humid environment which is ideal living conditions for fungus. Your hands are out all day, breathing. How many hours a day do you walk around barefoot? These circumstances make me think it is much more difficult to treat toenail fungus than fingernail fungus. I have been a bit on-and-off with my treatment, at most I have applied it once a day but I never had a layoff of more than a week or two, I did however not see any significant improvement (3 nails seem healthy, the others are bad)so this year I simply stopped doing it and was thinking about what I was going to try next.
When I stopped treating it completely I noticed it actually went from not getting any better to getting WORSE. I don't know, but I assume the gel, as I use it, on me, was able to keep the fungus somewhat in check although not cure it, so I started using it again just for precautionary reasons and now I apply it maybe 2-3 times a week. I will move on to another procedure but I just have to settle on one. I hate spending time every day over several months on something that had no hope of working in the first place, and filling the wallets of inhuman charlatans and quacks, such as the people behind the zetaclear scam (get a job, you zetaclear people) is something I really would hate to do, see my blog on fake remedies such as zetaclear: http://battlenailfungus.blogspot.se/2010/10/popular-and-heavily-advertised-fungus.html .
I will drop back quite soon with a new treatment regimen for me personally and I will keep you updated on my progress/regress. I have just been lost for some time and holding out hope for my old treatment to keep working wonders on other parts of my body, but I will have to find something else. As said before, I make zero cents off of this blog and I will never do anything to promote a non-effective, heavily advertised remedy that contains only vinegar, water and perfume. Whatever I choose to try will be given a lot of thought, researched, and viewed in a scientific way.
I hope as many as possible choose to follow this blog because, no matter how rarely it happens, I will post only correct information regarding my progress and current treatment methods.
måndag 21 maj 2012
I had a request for a description of the "dremel-like" machine I was using to file down my nails, well, here it is. There is nothing fancy about it, just an old high-speed drilling machine with different tools to insert into the chuck. The 2 upper tools are the ones I use, and the one on the top does 90 % of the work, the other one is just for the last piece of the nail close to the cuticle.
It has adjustable speed, normally I start out on slow speed and increase it slightly when I get into it (and bored). It is a tedious process but I recommend doing one foot and maybe the other one the next day, or your back may start to hurt and you will not be too thorough anymore....
I would say any similar machine will do, for example the cheap ones off ebay since it requires no engine power or super speed. Get for example the one on http://www.ebay.com/itm/DREMEL-400-XPR-Rotary-Tool-With-Accessories-And-Paperwork-New-Exec-Condition-/160802040751?pt=LH_DefaultDomain_0&hash=item25708c6baf or try maybe this one, even cheaper: http://www.ebay.com/itm/New-Cordless-Rotary-Tool-40pc-Kit-Dremel-Tool-Bits-Fit-Dog-Nail-Groomer-Grinder-/170843162711?pt=LH_DefaultDomain_0&hash=item27c70bc857
If you get just any tool and it does not carry the suitable sanding tips you see in the pic (the top one the most important one, it also works just fine without the pointy tip, you can use a cylinder-shaped one), just go to your local hardware store and ask for dremel acessories and they will most likely have a big shelf with them. They are expensive, but only one is not expensive...
There you go, good luck. =)
måndag 26 mars 2012
Spambots
(The website adresses have been distorted so their google results won't be helped. Thanks to Lee for the advice)
fredag 19 augusti 2011
Just dropping by: Scholl fungal nail treatment
onsdag 23 februari 2011
tisdag 22 februari 2011
Zetaclear scam. And other stuff. And an interesting tale...
As you understand, I am not associated with any drug manufacturer and I make zero money off of this (even if I did, the number of viewers could never make me a cent) so the only 2 reasons I write is: 1. I want others to be helped with a problem with which I am more than familiar. and 2. I am annoyed with people who does not want to help but only want to make money off of people remaining unhappy, such as the people behind the zetaclear scam. If you see any ads whatsoever they are Blogger's own ads and not mine.
When you read an internet tale about somebody who had tremendous success with a nail fungus treatment you should read it, but read it with an ounce or two of healthy, sensible scepticsism (sp?). It could be completely true. It could be completely true. The statement could be truthful, but we don't know the poster. We don't know his or hers life, we have not seen their nails, before or after. If they post pics, we don't know if it is their nails.
So should we just disregard everything we read? Absolutely not. But we should make asensible decision based on what we know, and if it something that should be checked out, give google a minute and check it out.
Could there be bias? Most of us have probably sometime taken a remedy, or a drug, or knocked on wood, or done something that we really wanted to work, and made ourselves believe it did. Only in some time did we realise it didn't, and we were only fooling ourselves. If you don't know the basic principles about the placebo effect I strongly recommend you to search and find out about it. When people really, really want to be helped they tend to convince themselves that they really are being helped, and only in retrospect do they find out that they only wanted to believe, but their nails or whatever still looked the same. A nail could be 100 % infected but start to lose a bit of the yellow, and you would think it is getting better, a small change becomes a big change in your mind when it may in fact be just the normal things that go on in a nail ravaged by fungus.
Could the poster be a scammer? It only takes minutes to write a post. Could there be a manufacturer of a drug posting as a pretend nail fungus sufferer? Or a person who sells said drug pretending to be a "patient", writing a fake review? Maybe even a spambot, automatically writing a nonsensical post? We don't know. But it is good to think about the possibilities, and know that we don't know......
You are unlikely to find deliberately falsified success stories about conventional treatments manufactured by large established companies, simply because they probably would not go through the hassle. Their drugs have passed all the scientific trials, went on market, are sold in state pharmacies (where I live) and their companies make profits in millions and millions of dollars. If even a thousand people buy their drug because of a fake post it is not enough to make an impact on their overall profit. They simply will not bother. If they wanted to go on forums and blogs marketing their drugs they could do it more easily and effectively and point to all the scientific trials that showed their drug had positive results, if it hadn't, they would be unable to market it. If it hadn't, their reputation would suffer, and money would be lost in the millions.
What about smaller maufacturers that make drugs that are outside of the established medicine(which is just an elaborate way of saying "NOT proven to work at all")? They have enormous reasons to create scams, their sales could increase tenfold if marketed correctly.
These companies may often, or seldom use these methods. But it is important to know that when reading a post, and you don't know the person writing it, the poster may have had something to gain from people believing it.
If he had nothing to gain, he is unlikely to have gone through the hassle of writing a false post.
If he had something to gain, maybe he did write a false post.
The reason I pick out Zetaclear in the jungle of nonsense mumbo-jumbo nail fungus remedies is, as said before, because they make a ridiculously huge effort to put these false claims on the web. Nonyx is another one that only contains water and vinegar under fancy names, but the Zetaclear scam simply takes the price.
This post is long now and must be posted, see you later for the mentioned tale.... =)
onsdag 13 oktober 2010
Toenails
Left big toe, Amorolfine nail lacquer. Note how still-infected thicker nail has grown out halfway.
Right foot, daily application of lamisil single-dose 1 % solution, same stuff that left my fingernails 99% cured in about 4 months.
Right toenail, lamisil. Thick nail has grown out halfway. The red dots are marks from going a bit hard with the grinding machine
Will file them down again (not excited about it, it is a boring and tiring process) and continue treatment. The treatment that is least successful I will discontinue and I will keep doing what works, be it amorolfine or terbinafine. On the foot that is not doing best I will try a new treatment, not sure what yet. We'll see.
EDIT: I checked out my first post from august 2009 with pictures from then. I had forgotten how bad it was, my toenails have actually come a looong way! Both feet, although still infected, have improved enormously. Fantastic. :D
Popular and heavily advertised fungus remedies
Nonyx nail gel is manufactured by the Xenna corporation and seems to sell quite well. Here are the ingredients according to their own website:
* Deionized Water,
* Ethanoic Acid,
* Xanthan Gum,
* Fragrance
Deionized sounds fancy, but the thing is it is basically just clean water. Water that has gone through filters to remove any minerals in it, it is about as clean as distilled water but cheaper to produce in large quantities.
In short: it’s just water.
Ethanoic acid also sound fancy. Thing is: it is just another name for acetic acid. And acetic acid happens to be:
Household vinegar. So they could have just written “vinegar”.
Xanthan gum sounds really interesting and I had to check it out. This happens to be a normal, common food additive that is used for raising the viscosity of a fluid, in simple words: It is used for making stuff thicker. Kinda like gelatine in jello.
So what we are supposed to pay for here is really: Water, vinegar, thickener, all of which you probably have in your kitchen. And some perfume for the scent… 30-40 dollars for this.
I would not call this a scam since vinegar actually does clear away keratin debris buildup and seems to be able to kill fungal spores in the nail. But it is ridiculously expensive for a water-vinegar mixture and it is obvious why they choose not to write "common vinegar" on the bottle.
Zetaclear:
Zetaclear is a huge presence in the googlesphere, but as any other of these "treatments" it is not proven to be efficient in any studies whatsoever, consumers have nothing to base their opinion upon except the company's own information, and that information is false.
And there is a problem: Zetaclear is being marketed extremely aggressively and in a dishonest way. Google "zetaclear" and you get dozens (!) of URLs such as www.zetaclearwarning.com and www.zetaclearreviewssite.com . All of these are scams and it is very obvious as the so-called "reviews" are extremely shameless in their praise of the product. you can also find tests that claim to be objective but they also are manufactured to make Zetaclear look good. The internet image of Zetaclear is carefully designed to make it seem like it gets everything from ecstatic tales of success from customers to sound and sensible positive feedback from serious sources. Look around, browse around, it is ridiculous, the energy and time the people behind zetaclear has put in to create all these websites.
AND it is a homeopathic remedy. As most people know by now, homeopathic treatments are water with no active substance in it, and it 100 % unsuccessful in treating anything apart from its placebo-effect. If you think it will cure your muscle tensions, you may relax, and praise the treatment. But it is still just water, and you are fooled. They are always diluted to the point that you would need to drink the atlantic ocean full of the liquid to get even one molecule of the claimed ingredients in your mouth.
It does actually contain something though, 10 % Undecylenic Acid, which is an older substance and not as effective as newer stuff like griseofulvin and terbinafine, but at least it is there, and can be effective. http://faculty.swosu.edu/scott.long/phcl/antifung.htm
Not much more to say about it, Zetaclear is the most obvious scam of them all. On http://lee.org/blog/2009/05/02/zetaclear/ there is a discussion between people who are frustrated by this shameless and elaborate scam, drop by and comment. The company behind zetaclear are making a profit off people's desperate wishes to get well.
fredag 8 oktober 2010
Pics
These pics happen to be 3 weeks old but nothing has changed since. On the pointer finger there is some persistent fungus to one side but it does not seem to grow so I leave it for now. I keep treating all fingers every day, the treatment is simple and only takes seconds so it is not any more hassle than it is brushing one's teeth in the evening.
Although I would like to eradicate the last tiny parts of fungus also I am extremely pleased and relieved with now having normal nails. It became a spare-time obsession/hobby to find a procedure that worked for me and be able to have clear nails again, and now I have the same nails I had 5 years ago. Success!
Nail fungus sufferers get various degrees of infection and it shows itself in different ways. Sometimes it does, as in my case, get ugly and nails are not only discolored and thickened but very deformed and loosened from the nail bed. When they are like this and stay like this for years you may get the idea that the nail has "forgotten" how to grow normally and will forever grow abnormally. This is not the case. The nail grows in a genetically coded manner just like skin and hair, and fungus only disturbs its pattern, it does not destroy it. Remember this when you treat your nails because it helps your motivation: they can be completely normal again.
As far as treatments go: the query "nail fungus treatment" gives 623 000 hits on google as I type this. Hundreds of millions of people worldwide probably have onychomycosis, it is a condition that is not harmful (it really isn't) so it is not at the top of the medical community's agenda, but it is a cosmetical problem for very, very many people. AND the available drugs are not yet perfect, oral Lamisil only cures about 50 % of the clients, so the market for so called "alternative" remedies is enormous. Very lucrative.
Very lucrative indeed.
And where there is money there will always be crooks. I mentioned this in an earlier post:
I estimate at least 90 % of those to be either useless or flat-out cons. It is sooo easy to mix up some stuff and call it a "nail fungus remedy" and mix in some reassuring words like "all natural", "proven to work" (implying it has been scientifically tested and verified which it never has, and if it was, it was proven to be completely ineffective), "thousands of satisfied customers" (show me the evidence), "guaranteed to cure nail fungus" (if it IS guaranteed, then YOU, as manufacturer are guaranteed to make a huge fortune, so why do you mess about on an obscure website?), "contains essential oils" etc etc etc....
For example, oil of oregano is a popular ingredient in many such remedies, on the basis that it is an all-round cure for pretty much everything and have been used by everybody since forever. Still, there is not ONE scientific study that shows that it has any antifungal properties apart from that when you keep it concentrated in a test tube and you toss fungal spores in there, yeah, the spores die. On the skin or nails it has shown no efficacy at all in studies.
Know this: conventional medicine has the best chance to help you, because it has by far the best track record. Even if a conventional drug only gives you 50 %, the alternative drug will give you a much lower chance of success. Remember:
If the alternative remedy was tremendously effective, it would be an instant hit and it would be all over the world in months. If you have an astonishing product you will not NEED to advertise on obscure websites.
Moral of the story is: IF you choose to use alternative treatments, consider using them in conjunction with treatments that are actually proven to actually be effective.
fredag 1 oktober 2010
Just dropping by
I still pursue the treatment, Amorolfine nail laquer on left foot, lamisil on right foot, and lamisil on fingernails. Although my ambition is twice-a-day application it turns out to be once a day normally.
This is actually something you should keep in mind when analyzing your results from treatments: be honest to yourselves. If you did not use the remedy as recommended or as often as recommended, then you cannot comment on the efficacy of this remedy. You could, but it would be irrelevant. You can only give an educated opinion on the results of the drug after NOT being used in the recommended way. If you were told to apply NalioClean twice a day for 6 months and you only did it for 3 months, then you can say "it works!" if it unexpectedly did work after that short time, but you cannot say that "it didn't work", because you did not follow the guidelines.
I will not post any pictures tonight either, but within one week they should be online. Verbal description: Not 100 % clear, but extremely close. Two of my fingers have tiny lines that show fungus 1-2 mm behind the nail edge now. I cant bring myself to wear the nails down more, I will see what happens. If the fungus grows, I will get aggressive again, but for now it seems to occupy a small area and maybe it will go away with continuous treatment and no further nail debridement.
Gotta go now, back soon!
torsdag 12 augusti 2010
On with the show
On the other 3 fingers I noticed the fungus was getting hold once more at the tips, so I filed that away. It kinda sucks when you are so close to the end but there is no way but the hard way, take away the bad, or it will keep infecting the good. What is a few more weeks when you have had the problem for years? And although the lamisil gel (NOT the cream) is expensive it really last for a long time, 14 nails I have been able to treat for over a month with 1 tube which is about 25 USD.
My toenails I filed down completely once more as the treatment was not as successful there. I could not bring myself to take them away completely. It is damn hard work to file down all the way to the nail bed since you want to be careful not to hurt yourself, and it is a time-consuming procedure as it is. But they are thin, thin now, and I treat my right foot twice a day now with the Lamisil. On my loeft foot I use Amorolfine nail laquer, mostly because I still have half a bottle left and I should use it up since it cost a fortune. When it is all out I will evaluate which foot has had the most progress.
In my next post I will post before- and afterpictures of the filing process and some pointers on how to go about it.
onsdag 4 augusti 2010
My procedure
So this is what finally got me progress, after using it in a creative and not doctor-recommended way. It is late and I will only make a quick update here by pasting some of what I have written in the awesome information source that is Lee's blog at http://lee.org/blog/2009/05/14/nonyx-nail-gel-part-2/comment-page-1/#comment-291999 . Forgive me if this post seems like a cut and paste job....
For years the look of my horrible nails have made me feel bad about myself. A couple of months ago I did something radical: I took my microdrill, put a sand tip on it (for marking tools and stuff) and slowly but surely, for hours and hours, wore all my toenails down to nothing, and also my thumbnail. This nail was horrific at the time as it had rapidly gotten worse and was more or less loose all the way back to the base. With drills, knives and the motor drill with different tips I methodically wore it down till I was on bare skin. A few times it hurt and there was some minor bloodshed when I got overexcited but it is really possible if you take the time!
On the bare nail bed I have since then applied 2-3 times a day Lamisil single dose, the FOOT fungus solution that contains terbinafine and is supposed to only be used once and not to be repeated. =) My toenails I cannot judge yet (though the nail bed looks nice) but my thumb IS ALMOST COMPLETELY GROWN OUT ALL HEALTHY. After all these years!
I firmly believe the lamisil is responsible for the improvement I see. I have not used itraconazole for over a month (although I must say the itraconazole seemed to have some independent success with the other nails as I tried this out only on the thumb to start with. As my success with the thumbnail was instantaneous and obvious I went on with the other nails in the same way) but the nails keep getting better. The stuff works like a charm now that I expose the nail bed to it.
The stuff is expensive by weight, but it lasts for a long time…. I have now used less than 1,5 tubes in the last 2 months, and I applied it on 10 toenails pretty much every day and on 4 fingernails 2 times every day. The tubes are about 25 USD a piece, and 4 grams. You could make a tube last 2 months which by this price would cost you maybe 13 bucks a month, surely you can spend that?
After a while the layer can turn a shiny greyish colour, especially on small depressions in the nail, but that is no problem, it only shows that you have a nice and thick layer of the stuff working constantly.
From time to time, maybe every 2 weeks I scrape the rubbery grey stuff off and clean the nail, this only takes seconds, then I just stick with the process.
There you go. =)
söndag 1 augusti 2010
lördag 24 juli 2010
Success!
I will make an extensive post with pics and descriptions of what has worked tonight.
Much love
Fungus
tisdag 30 mars 2010
Lasers
My doctor took me off Terbinafine after 6 months saying that it simply did not work. He was correct, because it didn't. My nails did not really get any better. Had it been my decision I would have stuck with it because I did not feel bad from it and I want to do everything I can to fight this infection, even if we can't say if one particular part in a multi-treatment works at all. If it doesn's harm me, let me stick with it.
After that nothing much happened for a couple of months. But now things are getting worse.... My thumbnail is horrible, almost completely loose. It is uncomfortable and it is actually painful. This has never been painful before. There is a numbing sensation of pain where the loosened nail meets the finger. As of now, I still stick to my amorolfine nail lacquer once a week, and terbinafine cream every day. I dropped vinegar again because I suspect it may not be good for my nails (what do I know) and back to sodium benzoate. It feels more gentle on the skin and does not produce that tingling sensation that vinegar does, I don't know if maybe the vinegar has been too hard on the nail bed, actually helping the infection.
Lasers are quite hot at the moment (haha). PinPointe and Nomir claim extraordinary results with their laser treatments for onychomycosis. However, these treatments are yet to be proven effective in quality independent studies. Nomir with their Noveon foot laser expected approval from the north american food and drug-administration in 2009, but so far no luck as far as one can see on their webpage.
Pinpointe boast with extraordinary claims, and I think one should expect these treatments to be effective to some extent, because if they did not do anything whatsoever they should not be around still. However, we don't know HOW effective they are until scientific independent studies have been done to a larger extent. As of now the treatments are fairly new (a couple of years) and the claims should be taken with a grain of salt.
That being said, I would gladly try it out for 1000 US$ if it was available in my neighbourhood. It looks rather promising on paper, and if it is effective it has huge potential considering it is non-toxic and it does not demand much of the patient when it comes to long-term labor.... Stay clean and disinfect your clothes and shoes, sounds better than for example soaking your feet in vinegar for several minutes twice a day......